Table 1:
Literature review of IDH2-mutated sinonasal carcinomas, confirmed by molecular or diagnostic immunohistochemical markers and their histopathologic classification.
| Author No. of patients |
SNUC-like | LCNEC-like | PDC-like | HG-Non-ITAC |
|---|---|---|---|---|
| Dogan et al.a 30 patients |
22 | 5 | 3 | - |
| Mito et al. 26 patients |
23b | - | 3c | - |
| Riobello et al. 14 patients |
9 | 2 | 1 | 2 |
| Jo et al. 6 patients |
6 | - | - | - |
| Libera et al. 5 patients |
2 | 3 | - | - |
| Heft Neal et al. 1 patient |
1 | - | - | - |
|
| ||||
| Total (82 patients) |
63 | 13 | 4 | 2 |
a
Including 4 articles with non-overlapping cases;
b
14 cases confirmed by immunohistochemical markers only;
c
1 case confirmed by immunohistochemical markers only; SNUC: sinonasal undifferentiated carcinoma; LCNEC: large cell neuroendocrine carcinoma; PDC: poorly differentiated carcinoma; HG-Non-ITAC: high grade non-intestinal-type adenocarcinoma.