Skip to main content
. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Mol Genet Metab. 2022 Nov 9:106963. doi: 10.1016/j.ymgme.2022.11.002

Table 3.

Changes in the fraction of cytoplasm volume of SSCE occupied by GL-3 inclusions, as assessed by electron microscopy, from baseline to Weeks 26 and 156.

Fraction of cytoplasm volume of SSCE occupied by GL-3 inclusions (electron microscopy)

Baseline Week 26 p-value Week 156 p-value

N 9 8 6
Value
 Mean (SD) 0.29 (0.03) 0.23 (0.04) 0.18 (0.03)
 Median (range) 0.30 (0.25 – 0.33) 0.24 (0.17 – 0.28) 0.19 (0.14 – 0.21)
Change from baseline -
 Mean (SD) - −0.06 (0.03) 0.0010 −0.12 (0.04) 0.0008
 Median (range) - −0.06 (−0.10 – 0) −0.13 (−0.16 – −0.05)
% Change from baseline
 Mean (SD) −21.09 (11.42) −38.74 (11.69)
 Median (range) −19.57 (−33.8 – 0) −40.00 (−51.1 – −19.9)

GL-3, globotriaosylceramide; SD, standard deviation; SSCE, superficial skin capillary endothelium.