Table 3.
Fraction of cytoplasm volume of SSCE occupied by GL-3 inclusions (electron microscopy) | |||||
---|---|---|---|---|---|
| |||||
Baseline | Week 26 | p-value | Week 156 | p-value | |
| |||||
N | 9 | 8 | 6 | ||
Value | |||||
Mean (SD) | 0.29 (0.03) | 0.23 (0.04) | 0.18 (0.03) | ||
Median (range) | 0.30 (0.25 – 0.33) | 0.24 (0.17 – 0.28) | 0.19 (0.14 – 0.21) | ||
Change from baseline | - | ||||
Mean (SD) | - | −0.06 (0.03) | 0.0010 | −0.12 (0.04) | 0.0008 |
Median (range) | - | −0.06 (−0.10 – 0) | −0.13 (−0.16 – −0.05) | ||
% Change from baseline | |||||
Mean (SD) | −21.09 (11.42) | −38.74 (11.69) | |||
Median (range) | −19.57 (−33.8 – 0) | −40.00 (−51.1 – −19.9) |
GL-3, globotriaosylceramide; SD, standard deviation; SSCE, superficial skin capillary endothelium.