Figure 8.

In vivo efficacy of high-intensity electrical biofilm treatment system using a type II diabetic mouse-based wound model infected with MRSA biofilms (n=3). (A) Experimental timeline and schematic illustration of our system setup on diabetic mouse (Created with BioRender.com). (B) Representative photographs of MRSA biofilm-infected wounds in different treatment groups. (C) Representative photographs of bacterial colony cultured from skin wounds at 24 h after different treatments. All tissue homogenates were diluted 10² times with PBS before plating. (D) MRSA bacterial count in skin wounds measured at 24 h after different treatments. (E) MRSA bacterial count in skin wounds measured at 7 days after treatment. (Scale bar: 3 mm)