Table 4.

Lowest binding energies of studied compounds with the proteins.

Protein	Free Energy of Binding (Kcal/mol)
	Control	Naringin	Eicosane	Octacosane
COL1	−10.16	−9.06	−5.99	−6.32
COL2	−6.48	−9.37	−6.42	−5.83
COL3	−7.29	−11.32	−6.66	−7.05
STRO1	−9.75	−8.87	−6.32	−6.36
STRO2	−10.50	−8.54	−6.75	−6.40
STRO3	−16.31	−7.88	−6.27	−4.77
Matrilysin	−2.93	−7.43	−4.66	−4.14
Metalloelastase	−10.86	−9.68	−6.81	−6.77
Metalloproteinase	−2.98	−4.47	−1.49	−0.86
GEL A	−4.66	−7.56	−5.75	−6.51
GEL B	−12.06	−9.33	−8.00	−6.80