| CBD | Cannabidiol |
| THC | Tetrahydrocannabinol |
| AChE | Acetylcholinesterase |
| BuChE | Butryrylcholinesterase |
| AD | Alzheimer’s disease |
| γ- secretase | Gamma-secretase |
| BACE-1 | Beta secretase-1 |
| ADMET | Absorption, Distribution, Metabolism, Excretion and Toxicity |
| THCV | Tetrahydrocannabivarin |
| iGEMDOCK | A Graphical Environment for Recognizing Pharmacological Interactions and Virtual Screening |
| GPR55 | G protein-coupled receptors 55 |
| GPR3 | G protein-coupled receptors 3 |
| NF-κB | nuclear factor κB |
| PPARγ | peroxisome proliferator-activated receptor γ |
| GPCRs | G protein-coupled receptors |
| BBB | Blood brain barrier |
| APP | Amyloid precursor protein |
| GPP | geranyl diphosphate |
| OLA | olivetolic acid |
| NFT | neurofibilliary tangles |
| Aβ | beta-amyloid |
| sAPP-β | soluble amyloid precursor protein β |
| CYP2D6 | Cytochrome P450 2D6 |
| CYP3A4 | Cytochrome P450 3A4 |
| P450s | cytochrome P450 enzymes |
| hERG | human ether-a-go-go-related gene |
| LD50 | lethal dose 50 |
| VDW | van der Waals interactions |
| HB | hydrogen bonds |
| SHY5YAPP+ cells | SH-SY5Y cells transfected with the amyloid precursor protein |
| CASTp | Computed Atlas of Surface Topography of proteins |
| Ki | inhibition constant of enzymes |
| Δ G | Gibbs free energy |
| TE | electrostatic forces |
| Kcal/mol | kilo-calorie per mole |
| PAINS | Pan Assay Interference Compounds |
| TPSA | topological molecular polar surface area |
| ClogP | log(coctanol/cwater) |
| HIA | human gastrointestinal absorption |
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