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Analysis of Pharmacokinetic properties and Protoxicity of three CBD analogues.
| Compound | Mw | HA | HD | Absorption | Lipinski’s Rule Violation | Solubility | BBB Permeability | CNS Permeability | CYP2D6 | LD50 (mg/kg) | Toxicity Class |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cannabidiorcol | 254.3 | 2 | 1 | 92.851 | 0 | −4.599 | 0.397 | −1.368 | NO | 800 | 4 |
| THCV | 286.4 | 2 | 1 | 91.821 | 0 | −4.403 | 0.336 | −1.99 | NO | 482 | 4 |
| Cannabinol C2 | 268.4 | 2 | 1 | 93.96 | 0 | −4.834 | 0.5 | −1.32 | NO | 1310 | 4 |
