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. Author manuscript; available in PMC: 2023 Feb 11.
Published in final edited form as: J Pathol. 2020 Jul 3;251(4):400–410. doi: 10.1002/path.5474

Figure 1.

Figure 1.

3D image of adenocarcinomas. (A) The main tumor was composed predominantly of tubules lined with irregular disorganized epithelium. The lumens in the tubules (arrows) were identified. Note the adjacent normal bile duct (arrowheads) (low-grade TB, confocal laser scanning microscope). (B) The main tumor was composed predominantly of complex interconnecting cords (arrowheads) (high-grade TB, confocal laser scanning microscope). (C) The main tumor and protrusions (surface rendering image). (D) Higher magnification of the periphery of tumor showing protrusions. Protrusion may form tubule (arrows) or cords (arrowheads) (surface rendering image, scale bar, 100 μm).