Figure 2.

Schematic illustration of in vivo experimental design. (A) Schematic diagram of animal model showing DMM-induced molded in the right hind limb and treated by oral administration. (B) Position of the femur, tibia, and medial meniscus in the knee joint. (C) Mice were pre-gavaged for 2 weeks, and then, DMM surgery was performed to establish the OA model, and tissue samples were harvested every 2 weeks from the fourth week after surgery for subsequent analysis. The number of samples in each group is expressed as an n value.