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. 2023 Feb 1;15(3):743. doi: 10.3390/nu15030743

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© 2023 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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SFN ameliorates intestinal histopathology and improves intestinal permeability in HFHFr mice. (A) Representative images of colon tissues stained by H&E staining in mice (n = 6). (B) Relative mRNA levels analysis of ZO-1 and Claudin-4 in colon tissues (n = 6). (C) Representative images of immunohistochemical staining of ZO-1 in colon samples (n = 6). The scale bar is 50 µm. (D) Quantification of immunohistochemical staining for ZO-1 (n = 6). (E) Serum LPS concentration of each group (n = 6). Data are shown as mean ± SEM. * p < 0.05, ** p < 0.01 compared with HFHFr.