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. 2023 Feb 3;28(3):1498. doi: 10.3390/molecules28031498

Table 1.

Potential factors that increase the chances of obtaining breast cancer with examples.

Factors Examples
Heredity and genetic factors Family history and breast cancer-causing gene mutation, pathogenic mutations in cancer-predisposition genes, and common single-nucleotide polymorphisms linked to breast cancer
Menstruation-related Age of menarche and later age of menopause
Reproduction-related Nulliparous, postponement of having firstborn, low rate of reproduction, and low rate of breastfeeding
Exogenous hormone consumption Oral contraceptive medication, menopausal hormone therapy, and hormone replacement therapy
Nutrition Alcohol consumption, high trans-fat content food consumption, and smoking habit
Anthropometry Obesity, high body mass index (BMI), high weight gain, and body fat distribution
Physical inactivity Lack of routine exercise or bodywork
History of breast pathologies Atypical hyperplasia, lobular carcinoma in situ, and high mammographic density
Exposure to therapeutic radiation Therapeutic chest radiation for the treatment of Hodgkin’s disease