Heredity and genetic factors |
Family history and breast cancer-causing gene mutation, pathogenic mutations in cancer-predisposition genes, and common single-nucleotide polymorphisms linked to breast cancer |
Menstruation-related |
Age of menarche and later age of menopause |
Reproduction-related |
Nulliparous, postponement of having firstborn, low rate of reproduction, and low rate of breastfeeding |
Exogenous hormone consumption |
Oral contraceptive medication, menopausal hormone therapy, and hormone replacement therapy |
Nutrition |
Alcohol consumption, high trans-fat content food consumption, and smoking habit |
Anthropometry |
Obesity, high body mass index (BMI), high weight gain, and body fat distribution |
Physical inactivity |
Lack of routine exercise or bodywork |
History of breast pathologies |
Atypical hyperplasia, lobular carcinoma in situ, and high mammographic density |
Exposure to therapeutic radiation |
Therapeutic chest radiation for the treatment of Hodgkin’s disease |