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. 2023 Feb 3;28(3):1498. doi: 10.3390/molecules28031498

Table 3.

The approved liposome-based delivery systems are used as treatments against breast cancer [47].

Use of Liposomes in Breast Cancer Delivery System [48,49]
Name Year Approved Content within Applications Lipid Composition
Doxil 1995 Doxorubicin Ovarian, breast cancer, and Kaposi’s sarcoma HSPC:Chol:PEG 2000-DSPE
Myocet 2000 Doxorubicin Metastatic breast cancer EPC:Chol
Lipo-dox 2012 Doxorubicin Breast and ovarian cancer DSPC:Chol:PEG 2000-DSPE

HSPC = L-α-phosphatidylcholine, hydrogenated (Soy), Chol = Cholesterol, PEG 2000-DSPE = PEGylated derivative of 1,2-distearoyl-sn-glycero-3-PE, DSPC = Distearoylphosphatidylcholine, EPC = 1,2-dioleoyl-sn-glycero-3-ethylphosphocholine.