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(A). Immunohistochemistry of the expression of cGMP in aortic tissue of diabetic rats: control rats a; diabetic rats b; fucoidan nanoparticles at doses of 75 c, 150 d, and 300 mg/kg BW e. (400×). (B). The number of cGMP-expressing cells that are immunoreactive. *, **, *** The columns with different letters show significance between groups (p < 0.05).
