Figure 9.

Ion channel malfunctions lead to physiological disorders such as cystic fibrosis. Current therapies are merely symptomatic. To solve this, the bilayer of liposomes is employed to integrate and deliver intact functional channels. Ion channels were collected in the form of membrane fragments to preserve their structure. Phospholipids chose to give liposomes a fusogenic property to place ion channels at their action site. This therapeutic principle was assayed microscopically and electrophysiologically.