Table 2. Demographic and clinical characteristics of the patients.
WHO, World Health Organization; ICU, intensive care unit; DM, diabetes mellitus, HT, hypertension; CAD, coronary artery disease; COPD, chronic obstructive lung disease; CLD, chronic liver disease; CKD, chronic kidney disease; AST, aspartate aminotransferase; ALT, alanine aminotransferase; CK, creatine kinase; LDH, lactate dehydrogenase; CT, computed tomography. † Moderate disease defined as a WHO score of ≤5. ‡Severe disease is defined as a WHO score of ≥6 (ICU admission or death).
Moderate disease†<br>(n = 65) | Severe disease‡<br>(n = 46) | All patients<br>(n = 111) | p-value | |
---|---|---|---|---|
Age | 57.54 ± 16.26 | 63.39 ± 15.50 | 59.96 ± 16.14 | 0.059 |
Gender (female) | 27 (41.54%) | 16 (34.78%) | 43 (38.74%) | 0.472 |
Symptoms at admission<br>Respiratory symptoms<br>Gastrointestinal symptoms<br>Myalgia | <br>40 (61.54%)<br>8 (12.31%)<br>13 (20.00%) | <br>38 (82.61%) <br>3 (6.52%) <br>3 (6.52%) | <br>78 (70.27%) <br>11 (9.91%) <br>16 (14.41%) | <br>0.017 <br>0.357 <br>0.046 |
Length of hospital stay (days) | 11 (4–37) | 19 (5–115) | 13 (4–115) | <0.001 |
Co-morbidities<br>DM (yes)<br>HT (yes)<br>CAD (yes)<br>COPD (yes)<br>CKD (yes) | <br>11 (16.92%)<br>23 (35.38%)<br>6 (9.23%)<br>6 (9.23%)<br>3 (4.61%) | <br>16 (34.78%)<br>22 (47.83%)<br>10 (21.74%)<br>2 (4.35%)<br>7 (15.22%) | <br>27 (24.32%)<br>45 (40.54%)<br>16 (14.41%)<br>8 (7.21%)<br>10 (9.01) | <br>0.031<br>0.188<br>0.065<br>0.466<br>0.089 |
Laboratory results on the test day<br>LDH (U/L)<br>Lymphocyte count (103/mL)<br>Lymphocyte percentage (%)<br>AST (U/L)<br>ALT (U/L)<br>CK (U/L)<br>Troponin I (ng/L)<br>Ferritin (mg/L)<br>Total bilirubin (mg/dL)<br>Direct bilirubin (mg/dL) | <br>311 (243–624)<br>1100 (300–3000)<br>19 (2.80–50)<br>36 (14–215)<br>30 (10–218)<br>74 (13–2031)<br>9.35 (3–589) n:42<br>370.50 (10–1850) n:58<br>0.60 (0.27–1.60)<br>0.10 (0.01–0.40) | <br>411.50 (281–881)<br>900 (100–2000)<br>14.50 (1.40–86)<br>57.50 (19–298)<br>45.50 (8–269)<br>79.50 (14–1143)<br>16 (3–500) n:45<br>461.50 (10–3689)<br>0.60 (0.18–3.37)<br>0.10 (0.01–2.44) | <br>350 (243–881)<br>1000 (100–3000)<br>17 (1.4–86)<br>39 (14–298)<br>36 (8–269)<br>75 (13–2031)<br>12 (3–589)<br>388 (10–3689)<br>0.6 (0.18–3.37)<br>0.1 (0.01–2.44) | <br><0.001<br>0.004<br>0.002<br><0.001<br>0.071<br>0.720<br>0.014<br>0.076<br>0.891 |
LDH isoenzymes<br>LDH1 (U/L)<br>LDH2 (U/L)<br>LDH3 (U/L)<br>LDH4 (U/L)<br>LDH5 (U/L) | <br>63.42 (41.65–141.65)<br>106.80 (39.53–219.45)<br>70.18 (29.07–151.63)<br>31.84 (12.97–71.20)<br>39.30 (13.54–217.55) | <br>83.25 (37.65–189.06)<br>142.09 (73.75–292.41)<br>91.29 (53.39–246.68)<br>43.24 (15.81–117.11)<br>48.92 (10.22–191.27) | <br>70.22 (37.65–189.06)<br>117.42 (39.53–292.41)<br>81.34 (29.07–246.68)<br>34.51 (12.97–117.11)<br>43 (10.22–217.55) | <br><0.001<br><0.001<br><0.001<br><0.001<br>0.024 |
Chest CT score<br>(0–25) | 9 (1–21) | 15 (5–25) | 11 (1–25) | <0.001 |