Table 1.
BMI, Body mass index; ACE, Angiotensin-converting enzyme<br>Continuous variables are presented as mean (standard deviation), unless otherwise specified (‡ median (interquartile range)); categorical variables are presented as absolute and relative frequencies. Continuous variables were compared by Student t test or by Mann-Whitney exact test, and categorical variables by Chi-square test.
| Parameter | Non-responders (n = 46) | Responders (n = 35) | p |
|---|---|---|---|
| Age, years | 61.9 (8.4) | 63.1 (7.1) | 0.511 |
| Gender, female/male | 17/29 | 13/22 | 0.986 |
| BMI, kg/m2 | 27.2 (4.0) | 28.2 (3.3) | 0.262 |
| Prevalence of smoker, n (%) | 7(15.2) | 12 (34.3) | 0.045 |
| Systolic blood pressure, mm Hg‡ | 130 (115–140) | 130 (120–140) | 0.276 |
| Diastolic blood pressure, mm Hg‡ | 80 (80–80) | 80 (80–80) | 0.142 |
| Diabetes mellitus, n (%) | 9 (19.6) | 11 (31.4) | 0.220 |
| Family history of coronary heart disease, n (%) | 21 (45.7) | 24 (68.6) | 0.200 |
| Previous myocardial infarction, n (%) | 26 (56.5) | 21 (60.0) | 0.269 |
| Atorvastatin, n (%) | 22 (47.8) | 22 (62.9) | 0.179 |
| Atorvastatin + octacosanol, n (%) | 24 (52.2) | 13 (37.2) | |
| Cardioprotective medications | |||
| Beta-blocker, n (%) | 38 (82.6) | 29 (82.9) | 0.977 |
| Calcium channel blocker, n (%) | 14 (30.4) | 8 (22.9) | 0.448 |
| Diuretics, n (%) | 28 (60.9) | 11 (31.4) | 0.009 |
| Antianginal drugs, n (%) | 21 (45.7) | 17 (48.6) | 0.794 |
| Aspirin/clopidogrel, n (%) | 40 (87) | 32 (91.4) | 0.526 |
| ACE inhibitors, n (%) | 39 (84.8) | 31 (88.6) | 0.622 |