Table 3.
Percentage changes in ASCVD risk and components according to post-supplementation 25(OH)D status.
| Post-Intervention Status | 25(OH)D < 75 nmol/L | 25(OH)D ≥ 75 nmol/L | p-Value * | ||
|---|---|---|---|---|---|
| % Change | p-Value | % Change | p-Value | ||
| All Participants | 105 | 25 | |||
| 25(OH)D (nmol/L) | 76 | <0.001 | 159 | <0.001 | <0.001 |
| Total cholesterol (mmol/L) | −0.2 | 0.95 | −2 | 0.71 | 0.54 |
| Triglycerides (mmol/L) | 12 | 0.98 | −2 | 0.58 | 0.06 |
| HDL cholesterol (mmol/L) | 11 | 0.01 | 12 | 0.009 | 0.16 |
| LDL cholesterol (mmol/L) | −3 | 0.35 | −3 | 0.62 | 0.86 |
| Glucose (mmol/L) | 3 | 0.56 | −2 | 0.83 | 0.79 |
| 10-year ASCVD risk (%) | −18 | 0.01 | −23 | 0.03 | 0.41 |
| Males | 49 | 9 | |||
| 25(OH)D (nmol/L) | 62 | <0.001 | 149 | <0.001 | 0.002 |
| Total cholesterol (mmol/L) | 3 | 0.39 | −0.4 | 0.95 | 0.97 |
| Triglycerides (mmol/L) | 7 | 0.83 | 3 | 0.44 | 0.36 |
| HDL cholesterol (mmol/L) | 6 | 0.02 | 8 | 0.02 | 0.46 |
| LDL cholesterol (mmol/L) | 3 | 0.51 | −3 | 0.85 | 0.56 |
| Glucose (mmol/L) | 4 | 0.57 | 8.4 | 0.13 | 0.35 |
| 10-year ASCVD risk (%) | −10 | 0.02 | −26 | <0.001 | 0.71 |
| Females | 46 | 16 | |||
| 25(OH)D (nmol/L) | 95 | <0.001 | 166 | <0.001 | <0.001 |
| Total cholesterol (mmol/L) | −3 | 0.38 | −2 | 0.59 | 0.49 |
| Triglycerides (mmol/L) | 2 | 0.73 | −7 | 0.31 | 0.07 |
| HDL cholesterol (mmol/L) | 16 | 0.03 | 15 | 0.03 | 0.38 |
| LDL cholesterol (mmol/L) | −8 | 0.05 | −3 | 0.51 | 0.79 |
| Glucose (mmol/L) | −2 | 0.83 | −9 | 0.22 | 0.32 |
| 10-year ASCVD risk (%) | −32 | 0.004 | −47 | 0.002 | 0.69 |
Note: Data presented as % change calculated by difference in mean or median levels/baseline mean or median level * 100. p-value * represents differences in percent changes in each variable in the two vitamin D improvement groups. p < 0.05 is considered significant.