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Effects of Oryza sativa L. cv. BB3CMU and BB4CMU extracts at 0.01 mg/mL on melanin content in B16F10 melanoma cells stimulated with 50 µM 3-isobutyl-1-methylxanthin (IBMX) for 48 h. Theophylline and arbutin (0.01 mg/mL) were used as standard controls. Cells cultured in the medium without treatment refer to the blank. Different letters within each treatment indicate significant differences (p < 0.05).
