Table 1.

NOX family and its regulatory subunit and expression in various tissues or cells.

NOX Family	Regulatory Subunit	Expression Observed in
		Tissue	Reference	Cells	Reference
1	NOXO1, NOXA1, p22phox, Rac	Smooth muscle Colon epithelial Uterus and placenta	[53] [54] [55]	Endothelial cells	[56]
				Cardiomyocytes	[57]
				Vascular smooth muscle cells	[58]
				Human aortic smooth muscle cells	[59]
				Smooth muscle cells	[60]
2	p22phox, p47phox, p40phox, and p67phox, Rac	Heart tissue	[61]	Endothelial cells, adventitial cells	[62]
				Cardiomyocytes, smooth muscle cells of the arteries	[63]
				Coronary microvascular endothelial cells	[64]
				Human umbilical vein endothelial cells	[65]
4	p22phox, Poldip2	Lung tissues Ovary and eye Fetal tissues Kidney	[66] [67] [49] [68]	Endothelial cells	[69]
				Cardiomyocytes, adventitial cells	[70]
				Vascular smooth muscle cells	[71]
				Human aortic smooth muscle cells	[72]
				Mesangial cells	[73]
				Hepatocytes	[74]
5	calmodulin-like domain with four Ca2+	Fetal, spleen and uterus tissues Lung, heart, thymus, liver, kidney, skeletal muscle	[49] [75]	Vascular smooth muscle cells Cardiomyocyte	[76] [70]