. 2023 Feb 3;28(3):1481. doi: 10.3390/molecules28031481

Table 2.

Cytotoxicity selectivity of compound 14b toward human non-tumorigenic cell lines and cancer cell lines ^a.

Cell Lines	IC₅₀, Mean ± SE (μM) ^b	Selectivity Ratio ^c
Hep-G2	0.074 ± 0.013	16.97
L-02	1.256 ± 0.214	16.97
C42B	0.051 ± 0.005	72.51
RWPE-1	3.698 ± 0.036	72.51
MCF-7	0.027 ± 0.006	231.7
MCF-10A	6.256 ± 0.311	231.7

^a Cell lines were treated with different concentrations of the compounds for 48 h. Cell viability was measured by a CCK-8 assay, as described in the Materials and Methods section. ^b IC₅₀ values are indicated as the mean ± SE (standard error) of at least three independent experiments. ^c Selectivity ratio = (IC₅₀ of human normal cells)/(IC₅₀ of corresponding cancer cell lines).