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. 2023 Feb 11;23:62. doi: 10.1186/s12890-023-02355-1

Table4.

Characterization of maternal mortality in pulmonary hypertension

Patients Etiology sPAP
(mmHg)
Delivery timing
(weeks)
Delivery mode Anesthesia Rescue therapy Timing after delivery Cause of death
1 PDA 105 34 Urgent cesarean Epidural-

dopamine + adrenaline

 + ventilator

3 days Severe preeclampsia, heart failure associated with multiple organ failure
2 PDAa 89 35 Urgent cesarean General-

nitric oxide + epinephrine + dopamine isoproterenol + 

norepinephrineventilator + CPR

10 days Persistent hypoxemia, circulatory collapse and hypoxic encephalopathy
3 VSD 57 33 Urgent cesarean General- epinephrine + dopamine + ventilator + CPR within 24 h Multiple organ failure, postpartum hemorrhage(1500 ml)
4 ASD 87 38 Urgent cesarean General-

dopamine + epinephrine

 + dopamine + ventilator

10 days Severe preeclampsia, circulatory collapse, hypoxic encephalopathy
5 VSDb 84 33 Planned cesarean Epidural- Nebulized iloprost + Nitric oxide + defibrillation 2 days Sudden ventricular fibrillation with RV systolic pressure as high as 132 mmHg

aleft-to-right shunting developed into right-to-left shunting or bidirectional shunting(Eisenmenger syndrome;bpostoperative pulmonary arterial hypertension; ASD atrial septal defect; PDA patent ductus arteriosus; VSD ventricular septal defect; sPAP pulmonary artery systolic pressure; CPR cardiopulmonary resuscitation