Table 7.
Indicators | Core tissue (A) | Liquid-based cytology (B) | Smear cytology (C) | P | P (A vs. B) | P (A vs. C) | P (B vs. C) |
---|---|---|---|---|---|---|---|
SS | |||||||
Sensitivity, % (95% CI) | 48.93 (40.56-57.30) | 60.71 (53.37-68.05) | 35.58 (25.95-45.21) | <0.0001 | 0.0051 | 0.0016 | <0.0001 |
Specificity, % (95% CI) | 100 | 100 | 100 | ||||
Accuracy, % (95% CI) | 50.86 (45.12-56.60) | 62.20 (56.63-67.77) | 37.91 (32.20-43.62) | <0.0001 | 0.0058 | 0.0019 | <0.0001 |
PPV, % (95% CI) | 100 | 100 | 100 | ||||
NPV, % (95% CI) | 7.14 (3.07-11.21) | 9.09 (3.97-14.21) | 5.49 (2.18-8.80) | 0.4842 | 0.5545 | 0.534 | 0.2274 |
SP | |||||||
Sensitivity, % (95% CI) | 41.43 (32.47-50.39) | 46.07 (37.47-54.67) | 44.53 (35.56-53.50) | 0.5302 | 0.2681 | 0.465 | 0.7176 |
Specificity, % (95% CI) | 100 | 100 | 100 | ||||
Accuracy, % (95% CI) | 43.64 (37.94-49.34) | 48.11 (42.37-53.85) | 46.74 (40.85-52.63) | 0.5421 | 0.2795 | 0.459 | 0.7439 |
PPV, % (95% CI) | 100 | 100 | 100 | ||||
NPV, % (95% CI) | 6.29 (2.69-9.89) | 6.79 (2.92-10.66) | 6.96 (2.99-10.93) | 0.9671 | 0.8514 | 0.8041 | 0.9515 |
WS | |||||||
Sensitivity, % (95% CI) | 48.57 (40.17-56.97) | 52.86 (44.82-60.90) | 40.66 (31.52-49.80) | 0.0145 | 0.3104 | 0.0613 | 0.0041 |
Specificity, % (95% CI) | 100 | 100 | 100 | ||||
Accuracy, % (95% CI) | 50.52 (44.78-56.26) | 54.64 (48.92-60.36) | 42.96 (37.20-48.72) | 0.0178 | 0.3192 | 0.0694 | 0.0051 |
PPV, % (95% CI) | 100 | 100 | 100 | ||||
NPV, % (95% CI) | 7.10 (3.06-11.14) | 7.69 (3.32-12.06) | 6.36 (2.72-10.00) | 0.8973 | 0.8443 | 0.7895 | 0.6428 |
Overall | |||||||
Sensitivity, % (95% CI) | 73.57 (67.55-79.59) | 76.79 (71.15-82.43) | 65.36 (58.47-72.25) | 0.0081 | 0.3786 | 0.0348 | 0.0029 |
Specificity, % (95% CI) | 100 | 100 | 100 | ||||
Accuracy, % (95% CI) | 74.57 (69.57-79.57) | 77.66 (72.87-82.45) | 66.67 (61.25-72.09) | 0.0087 | 0.3816 | 0.0363 | 0.0031 |
PPV, % (95% CI) | 100 | 100 | 100 | ||||
NPV, % (95% CI) | 12.94 (5.80-20.08) | 14.47 (6.56-22.38) | 10.19 (4.48-15.90) | 0.6654 | 0.7775 | 0.5498 | 0.3773 |
CI: Confidence interval, PPV: Positive predictive value, NPV: Negative predictive value, SS: Standard suction, SP: Stylet slow-pull, WS: Wet suction