Table 3.
Comparison of PsA versus vehicle control-treated hematological biochemical parameters glucose (GLU), aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), blood urea nitrogen (BUN), and creatinine (CREAT) in male Swiss albino mice. Data shown as mean ± SEM for n = 5/sex/group.
| Parameters | Control | 10 mg/kg | 250 mg/kg | 500 mg/kg |
|---|---|---|---|---|
| GLU (mg/dL) | 224.0 ± 4.8 | 294.0 ± 15.8 | 234.3 ± 11.8 | 236.8 ± 7.7 |
| AST (U/L) | 93.0 ± 10.2 | 115.0 ± 17.3 | 153.8 ± 8.8 | 105.8 ± 19.7 |
| ALT (U/L) | 31.8 ± 0.8 | 31.5 ± 2.9 | 41.8 ± 2.7 | 29.3 ± 1.2 |
| ALP (U/L) | 74.8 ± 1.4 | 70.8 ± 5.0 | 79.5 ± 4.1 | 76.8 ± 9.1 |
| BUN (mg/dL) | 24.3 ± 0.2 | 21.0 ± 1.6 | 22.8 ± 1.5 | 20.3 ± 0.5 |
| CREAT (mg/dL) | 0.2 ± 0.0 | 0.2 ± 0.0 | <0.2 ± 0.0 | 0.2 ± 0.0 |