Table 6.
Comparison of PsA versus vehicle control-treated hematological parameters white blood cell count (WBC), red blood cell count (RBC), hemoglobin count (HGB), hematocrit (HCT), mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), and platelet count (PLT) in female Swiss albino mice. Data shown as mean ± SEM for n = 5/sex/group.
| Parameters | Control | 10 mg/kg | 250 mg/kg | 500 mg/kg |
|---|---|---|---|---|
| WBC (103/μL) | 4.1 ± 1.2 | 4.6 ± 0.8 | 5.2 ± 1.9 | 3.1 ± 1.1 |
| RBC (106/μL) | 9.1 ± 0.7 | 9.1 ± 0.4 | 9.5 ± 0.9 | 10.0 ± 0.3 |
| HGB (g/dL) | 13.5 ± 0.5 | 13.4 ± 0.6 | 14.1 ± 0.7 | 15.0 ± 0.5 |
| HCT (%) | 47.3 ± 4.8 | 45.0 ± 3.1 | 46.3 ± 5.3 | 50.7 ± 2.8 |
| MCV (fL) | 51.8 ± 2.1 | 49.5 ± 2.7 | 48.7 ± 2.8 | 50.6 ± 1.3 |
| MCHC (g/dL) | 28.7 ± 2.3 | 30.0 ± 2.1 | 30.5 ± 2.3 | 29.6 ± 0.9 |
| PLT (103/μL) | 514.0 ± 117.6 | 587.5 ± 139.7 | 635.0 ± 133.2 | 409.0 ± 129.7 |