Fig. 6.

Freezing during reward/fear/safety sessions. A Freezing during the 20 s cue period across the 4 reward/fear/safety sessions in response to the reward (R; paired with sucrose), fear (F; paired with footshock), and safety (S; no sucrose or footshock) cues. For all groups freezing was elevated during the fear (F) cue (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 indicate within sex, within condition, between cue effects). In general, stress increased freezing to the reward and safety cues regardless of sex (#p < 0.05; ##, p < 0.01; ###, p < 0.001; ####, p < 0.0001 indicate within cue, within sex, between condition effects). In the first session (A), female no stress rats froze significantly more than male no stress rats ($p < 0.05 indicates within cue, within condition, between sex effects). Data are shown as mean % time spent freezing + / − SEM