Figure 8.
A schematic model illustrating APX1-mediated monitoring of the kinetics of long-lasting production of ROS in the cytosol. LPS, 3-OH-C10:0, or bacterial effectors trigger a long-lasting ROS burst in the cytosol. When ROS production is monitored by a luminol-based chemiluminescence assay, cytosolic APX1 serves as a catalyst for luminol oxidation. The model was created with BioRender.com.