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. 2023 Feb 11;24:32. doi: 10.1186/s12882-023-03082-9

Table 2.

Risk factors of MACE

Univariate analysis Multivariate analysis
HR 95% CI p HR 95% CI p
General parameters
 Age > 56,60 y 3.79 1.71; 8.40  < 0.01 2.47 1.05; 5.79 0.04
 Male sex 2.46 1.05; 5.79 0.04 - - -
Cardiovascular risk factors
 Arterial hypertension 1.33 0.18; 9.83 0.78 - - -
 Diabetes 1.87 0.76; 4.62 0.17 - - -
 Hyperlipidemia 1.00 0.40; 2.46 0.99 - - -
 Active smoking or smoking history 1.80 0.84; 3.87 0.13 - - -
Pre-existing conditions
 Coronary disease 12.89 5.77; 28.79  < 0.01 9.87 3.97; 24.51  < 0.01
 Prior myocardial infarction 4.40 1.87; 10.39  < 0.01 2.82 1.04; 7.63 0.04
 Atrial fibrillation 3.18 1.43; 7.06  < 0.01 - - -
 Prior stroke 1.24 0.29; 5.24 0.77 - - -
 Peripheral arterial disease 3.45 1.45; 8.16  < 0.01 - - -
Laboratory parameters
 Creatinine [mg/dl] 0.93 0.80; 1.08 0.36 - - -
 eGFR [ml/min/m2] 1.02 0.88; 1.19 0.80 - - -
 NT-proBNP > 4350 pg/ml 3.55 1.60; 7.88  < 0.01 3.04 1.29; 7.14 0.01
 Phosphate [mmol/l] 0.59 0.25; 1.37 0.22 - - -
 Calcium [mmol/l] 1.21 0.18; 8.16 0.85 - - -
 PTH [pg/ml] 1.00 1; 1 0.76 - - -
 Cholesterol > 200 mg/dl 2.59 1.17; 5.73 0.02 4.03 1.70; 9.56  < 0.01
 HDL-Cholesterol [mg/dl] 0.98 0.90; 1.06 0.57 - - -
 LDL-Cholesterol [mg/dl] 1.01 0.99; 1.02 0.48 - - -
 Triglycerides [mg/dl] 1.00 1; 1 0.07 - - -
 HbA1c [%] 2.24 0.63; 7.96 0.21 - - -
 Uric acid [mg/dl] 0.89 0.69; 1.13 0.33 - - -
 CRP [mg/l] 1.00 0.98; 1.02 1.00 - - -