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. Author manuscript; available in PMC: 2024 Jan 1.
Published in final edited form as: Neurosci Biobehav Rev. 2022 Dec 16;144:105006. doi: 10.1016/j.neubiorev.2022.105006

Table 5.

Key findings and study characteristics of studies on phthalate exposure.

First
author
(study
year)
Toxicant N Age at
toxicant
measure
Toxicant measure Age
at
MRI
MRI
measure
Exposure main effect
England-Mason et al. (2020) High and low molecular weight phthalates 76 Prenatal Spot urine 3 – 5 years FA and MD in major white matter tracts. HMWP exposure was associated with greater MD of the R IFO, R pyramidal fibers, and bilateral UF. Higher LMWP exposure was associated with reduced FA of the L ILF.
Park et al. (2015) Metabolites of DEHP and DBP 115 6 – 15 years Spot urine 6 – 15 years Whole brain CT Negative correlation between metabolites of DEHP and CT in the right middle and superior temporal gyri.

Note. See notes following Table 9 for table notes and a comprehensive list of abbreviations.