Table 1. The search strategy summary.

Items	Specification
Date of search	January 1st, 2021–May 1st, 2022
Databases and other sources searched	PubMed, Web of Science, Google Scholar
Search terms used	Search terms included “cell senescence AND idiopathic pulmonary fibrosis”, “aging AND idiopathic pulmonary fibrosis”, “alveolar epithelial cell AND cell senescence AND idiopathic pulmonary fibrosis”, “alveolar epithelial cell AND cell senescence AND lung disease”, “alveolar epithelial cell AND cell senescence”, “alveolar epithelial cell AND idiopathic pulmonary fibrosis”, “cell senescence”, “WNT/β-catenin AND cell senescence AND pulmonary fibrosis”, “PI3K/Akt AND cell senescence AND pulmonary fibrosis”, “mTOR AND cell senescence AND pulmonary fibrosis”, “NF-κB AND cell senescence AND pulmonary fibrosis”, “WNT/β-catenin AND cell senescence”, “PI3K/Akt AND cell senescence”, “mTOR AND cell senescence”, “NF-κB AND cell senescence”
Timeframe	2000–2022
Inclusion and exclusion criteria	Inclusion criteria: lung diseases associated with aging
	Exclusion criteria: research with similar conclusions
Selection process	Mingjin Tu independently selected and reviewed all initial articles, with additional review by Ting Wei and Yufang Jia. Ultimate final article inclusion was determined by all authors

PI3K/Akt, phosphatidylinositol-3-kinase/protein kinase B; NF-κB, nuclear factor kappa B.