TABLE 3.
Association of gene expression with genotypes in QTLs located on chromosomes 1, 5, and 16. These genes are located within the LD region that is defined as r2 > 0.6 with the top SNP for each QTL. Genes that have cis-eQTL are bolded. *denotes genes that lie just outside the interval of interest, but are included because of supporting evidence from prior publications.
| Gene name | eQTL top SNP | TSS position, bp | Log2 of Effect size | -log10(p) | -log10(p) threshold |
|---|---|---|---|---|---|
| Tyr | chr1:151274936 | 151,106,802 | -0.649 | 2.11 | 3.28 |
| Grm5 | chr1:151188824 | 151,207,846 | -0.502 | 1.72 | 3.42 |
| Ctsc | chr1:151908338 | 151,918,514 | 0.117 | 3.51 | 3.37 |
| Rab38 | chr1:152014155 | 152,072,716 | -0.158 | 1.42 | 3.45 |
| Tmem135 | chr1:152688130 | 153,096,225 | 0.210 | 0.63 | 3.61 |
| MGC94199 | chr5:23536473 | 23,358,464 | 6.644 | 1.25 | 3.68 |
| LOC102555924 | chr5:24663199 | 24,230,769 | 1.005 | 0.84 | 3.46 |
| Plekhf2 | chr5:24082110 | 24,255,922 | -0.264 | 3.38 | 3.50 |
| Ndufaf6* | chr5:24227315 | 24,320,804 | -0.516 | 2.38 | 3.52 |
| Angpt2 * | chr16:75564376 | 75,966,480 | -0.483 | 3.62 | 3.62 |
| Mcph1 | chr16:76216277 | 76,110,624 | 1.361 | 2.72 | 3.64 |
| Csmd1 | chr16:78525074 | 77,152,823 | -0.112 | 0.72 | 3.48 |