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. 2023 Jan 30;13:1109418. doi: 10.3389/fcimb.2023.1109418

Table 5.

Univariate and multivariate analysis for factors associated with CR-GNB infection in ICU patients.

Variable Univariate analysis Multivariate analysis
OR 95% CI p-value OR 95% CI p-value
History of recent hospitalization 2.363 1.212–4.608 0.012 - - -
Combination antibiotic treatment (X1) 3.994 2.084–7.656 <0.001 3.197 1.561–6.549 0.001
Duration of mechanical ventilation before the
occurrence of infective bacteria (days)
1.050 1.018–1.083 0.002 - - -
No. of types of antibiotics used 1.544 1.222–1.950 <0.001 - - -
Hospital-acquired infection (X2) 5.953 1.972–17.970 0.002 3.563 1.062–11.959 0.040
History of glucocorticoid use 2.546 1.189–5.451 0.016 - - -
History of carbapenem use 3.354 1.739–6.470 <0.001 - - -
History of central venous catheterization 3.131 1.661–5.901 <0.001 - - -
Duration of mechanical ventilation (days) 1.165 1.067– 1.272 0.001 - - -
Duration of mechanical ventilation ≥7 days (X3) 6.471 2.437–17.181 <0.001 5.096 1.865–13.923 0.001

CR-GNB, carbapenem-resistant gram-negative bacteria; OR, odds ratio; CI, confidence interval; -: variables that were excluded through the stepwise forward regression method.