The potency of IR-R@LIP/PFOB + Laser to introduce ICD and promote DC maturation in vivo. (a) Immunofluorescent images of tumor slices stained by CRT, HMGB1, and HSP70 (scale bar = 20 μm). (b–e) Representative flow cytometry plots of DCs in tumors, SLN, and spleen post various treatments (n = 3, ∗P < 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001). (f–g) Cytokine levels of TNF-α and IL-6 in serum detected by ELISA kits (n = 3, ∗∗∗P < 0.001).