Table 3.
Types of intervention for Crohn’s disease
| Intervention | |
| 5-aminosalicylic acid (5-ASA) | Mesalazine |
| Sulphasalazine | |
| Corticosteroids | Hydrocortisone |
| Methylprednisolone | |
| Prednisolone | |
| Budesonide-ileal release | |
| Antibiotics | |
| Probiotics | |
| Synbiotics | |
| Thiopurine | Azathioprine Mercaptopurine Thioguanine |
| Methotrexate | |
| Calcineurin inhibitors | Ciclosporin Tacrolimus |
| Advanced medical therapies | |
| Biologics-TNF | Adalimumab |
| Infliximab (intravenous and subcutaneous) | |
| Golimumab | |
| Biologics anti-integrin | Vedolizumab (intravenous and subcutaneous) |
| Cytokine inhibitors | Ustekinumab |
| Risankizumab | |
| Janus kinases (JAK) inhibitors | Tofacitinb |
| Filgotinib | |
| Upadacitinib | |
| S1P modulators | Ozanimod |
| Dietary interventions | Specialist or exclusion diets |
| Surgical therapies | |
| Haematological treatments | |
| Alternative therapies | |
When available, data on biosimilars will be grouped with that of the originator drug