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Benefits of exercise on the maintenance of local homeostasis and the involved mechanisms. Regular exercise at moderate intensity generally contributes to the maintenance of systemic homeostasis. ACE2 = angiotensin-converting enzyme 2; IFNγ = interferon-γ; IL = interleukin; miR = microRNA; NK = natural killer; TMPRSS2 = transmembrane protease serine 2; TNF-α = tumor necrosis factor-α; WBC = white blood cell counts.
