Measured variables
M F1	API mass hold-up of Feeder 1 (kg)
M F2	Excipient mass hold-up of Feeder 2 (kg)
ω F1	Screw rotation speed of Feeder 1 (rpm)
ω F2	Screw rotation speed of Feeder 2 (rpm)
F B1,out	Outlet mass flow rate of Blender 1 (kg/h)
C B1,out	Outlet API concentration of Blender 1
ω B1	Agitator rotation speed of Blender 1 (rpm)
Unmeasured Variables
F F1	Mass flow rate of Feeder 1 (kg/h)
F F2	Mass flow rate of Feeder 2 (kg/h)
F B1,in	Inlet mass flow rate of Blender 1 (kg/h)
C B1,in	Inlet API concentration of Blender 1
M B1,n	Mass hold-up of compartment n (kg)
F B1,n	Outlet mass flow rate of compartment n (kg/h)
C B1,n	Outlet API concentration of compartment n
Constants
${\omega }_F^{*}$, ${\omega }_{B1}^{*}$	Normal rotation speeds (rpm)
$M_F^{*}$, $M_{B1,n}^{*}$	Normal mass hold-ups (kg)
σ*, δ*	Variances of noise of state variables