TABLE 2.
CCHD Cases With One of the 7 Primary Screening Target Defects by Birth Year and Timing of Diagnosis Among Massachusetts Live Births
| Birth Year | Number of Live Births a | Primary Target CCHD Cases | Prenatal, b N (%) | In hospital, b N (%) | Delayed, N (%) | Primary Target CCHD Birth Prevalence c (95% CI) |
|---|---|---|---|---|---|---|
| 2004 | 78 062 | 81 | 38 (46.9) | 35 (43.2) | 8 (9.9) | 10.4 (8.2–12.9) |
| 2005 | 76 455 | 84 | 49 (58.3) | 28 (33.3) | 7 (8.3) | 11.0 (8.8–13.6) |
| 2006 | 77 237 | 84 | 52 (61.9) | 27 (32.1) | 5 (6.0) | 10.9 (8.7–13.5) |
| 2007 | 77 544 | 75 | 47 (62.7) | 25 (33.3) | 3 (4.0) | 9.7 (7.6–12.1) |
| 2008 | 76 572 | 69 | 50 (72.5) | 18 (26.1) | 1 (1.4) | 9.0 (7.0–11.4) |
| 2009 | 74 597 | 77 | 55 (71.4) | 15 (19.5) | 7 (9.1) | 10.3 (8.2–12.9) |
| Total | 460 467 | 470 | 291 (61.9) | 148 (31.5) | 31 (6.6) | 10.2 (9.3–11.2) |
Row percentages are presented. Percentages may not sum to 100 due to rounding. Primary screening target defects include dextro-transposition of the great arteries, hypoplastic left heart syndrome, pulmonary atresia, tetralogy of Fallot, total anomalous pulmonary venous return, tricuspid atresia, and truncus arteriosus.
From Massachusetts Registry of Vital Records and Statistics. Includes live births to Massachusetts residents that occurred in Massachusetts or Rhode Island. Rhode Island accounts for ~900 live births per year.
Cochran Armitage test for trend P < .002, 2-sided.
Per 10 000 live births. There was no significant linear trend.