TABLE 6.
aPR for Associations Between Demographic and Clinical Factors and Delayed Diagnosis Among Subgroups of CCHD Cases
aPR a (95% CI) for Delay b Excluding Diagnoses After 30 d, N = 848 | aPR a (95% CI) for Delay b Among Primary 7 Defect c Cases, N = 470 | aPR a (95% CI) for Delay b Excluding Prenatal, N = 436 | aPR a (95% CI) for Diagnosis > 3 d Versus ≤ 3 d, N = 916 | |
---|---|---|---|---|
Maternal age, y | ||||
15–24 | Reference | Reference | Reference | Reference |
25–34 | 2.2 (0.9–5.2) | 0.8 (0.3–1.9) | 1.0 (0.6–1.5) | 1.2 (0.9–1.8) |
≥35 | 1.8 (0.7–4.6) | 0.8 (0.3–2.3) | 0.9 (0.5–1.4) | 1.2 (0.8–1.9) |
Maternal race/ethnicity | ||||
Non-Hispanic white | Reference | Reference | Reference | Reference |
Non-Hispanic black | 0.7 (0.2–2.4) | 0.8 (0.2–4.0) | 1.2 (0.7–2.2) | 1.4 (0.8–2.3) |
Hispanic | 0.9 (0.4–2.0) | 0.7 (0.2–2.2) | 1.0 (0.6–1.7) | 1.0 (0.7–1.6) |
Asian | 1.9 (0.9–4.0) | 3.0 (1.0–8.9) d | 1.0 (0.6–1.9) | 1.4 (0.8–2.6) |
Other | 0.5 (0.1–2.5) | 1.9 (0.6–6.4) | 1.2 (0.6–2.4) | 1.0 (0.6–1.8) |
Maternal education, y | ||||
≥12 | Reference | Reference | Reference | Reference |
0–11 | 1.5 (0.6–3.6) | 0.8 (0.3–2.1) | 0.7 (0.4–1.3) | 0.8 (0.5–1.3) |
Region of residence | ||||
Boston | Reference | Reference | Reference | Reference |
Outside Boston | 1.5 (0.6–4.1) | 0.7 (0.2–3.0) | 1.6 (0.8–3.5) | 2.0 (0.9–4.2) |
Delivery hospital type | ||||
Level 3 | Reference | Reference | Reference | Reference |
Nonlevel 3 | 3.1 (1.8–5.2) d | 4.8 (2.1–11.1) d | 1.0 (0.7–1.4) | 3.6 (2.7–4.9) d |
Prenatal care insurance | ||||
Private | Reference | Reference | Reference | Reference |
Government/other | 1.3 (0.7–2.3) | 1.9 (0.8–4.6) | 1.1 (0.8–1.6) | 1.2 (0.9–1.7) |
Prenatal care initiation | ||||
First trimester | Reference | Reference | Reference | Reference |
After first trimester | 1.1 (0.5–2.3) | 1.5 (0.6–3.4) | 1.2 (0.9–1.7) | 1.1 (0.8–1.6) |
CCHD type | ||||
Nonisolated | Reference | Reference | Reference | Reference |
Isolated e | 2.0 (1.0–4.0) d | 0.9 (0.4–2.2) | 1.6 (1.0–2.5) d | 1.6 (1.1–2.2) d |
Gestational age, wk f | ||||
≥37 | Reference | Reference | Reference | Reference |
20–36 | 0.4 (0.1–1.2) | 0.4 (0.1–1.8) | 0.7 (0.4–1.2) | 1.1 (0.8–1.7) |
Plurality | ||||
Singleton | Reference | Reference | Reference | Reference |
Multiple | 1.0 (0.4–3.1) | 3.1 (0.9–10.4) | 1.2 (0.6–2.3) | 1.4 (0.9–2.3) |
Birth weight, g | ||||
≥1500 | Reference | Reference | Reference | Reference |
355–1499 | 1.2 (0.2–8.8) | NA | 0.5 (0.1–2.0) | 1.1 (0.5–2.2) |
NA, not applicable.
Adjusted model includes all demographic and clinical factors examined. Each individual variable is presented after controlling for all other variables in the model.
Diagnosed after discharge home following delivery.
Includes dextro-transposition of the great arteries, hypoplastic left heart syndrome, pulmonary atresia, tetralogy of Fallot, total anomalous pulmonary venous return, tricuspid atresia, and truncus arteriosus.
P < .05.
Includes cases with single CCHDs and cases with multiple cardiac defects.
Based on clinical estimate.