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. 2014 Aug;134(2):e373–e381. doi: 10.1542/peds.2013-3949

TABLE 6.

aPR for Associations Between Demographic and Clinical Factors and Delayed Diagnosis Among Subgroups of CCHD Cases

aPR a (95% CI) for Delay b Excluding Diagnoses After 30 d, N = 848 aPR a (95% CI) for Delay b Among Primary 7 Defect c Cases, N = 470 aPR a (95% CI) for Delay b Excluding Prenatal, N = 436 aPR a (95% CI) for Diagnosis > 3 d Versus ≤ 3 d, N = 916
Maternal age, y
 15–24 Reference Reference Reference Reference
 25–34 2.2 (0.9–5.2) 0.8 (0.3–1.9) 1.0 (0.6–1.5) 1.2 (0.9–1.8)
 ≥35 1.8 (0.7–4.6) 0.8 (0.3–2.3) 0.9 (0.5–1.4) 1.2 (0.8–1.9)
Maternal race/ethnicity
 Non-Hispanic white Reference Reference Reference Reference
 Non-Hispanic black 0.7 (0.2–2.4) 0.8 (0.2–4.0) 1.2 (0.7–2.2) 1.4 (0.8–2.3)
 Hispanic 0.9 (0.4–2.0) 0.7 (0.2–2.2) 1.0 (0.6–1.7) 1.0 (0.7–1.6)
 Asian 1.9 (0.9–4.0) 3.0 (1.0–8.9) d 1.0 (0.6–1.9) 1.4 (0.8–2.6)
 Other 0.5 (0.1–2.5) 1.9 (0.6–6.4) 1.2 (0.6–2.4) 1.0 (0.6–1.8)
Maternal education, y
 ≥12 Reference Reference Reference Reference
 0–11 1.5 (0.6–3.6) 0.8 (0.3–2.1) 0.7 (0.4–1.3) 0.8 (0.5–1.3)
Region of residence
 Boston Reference Reference Reference Reference
 Outside Boston 1.5 (0.6–4.1) 0.7 (0.2–3.0) 1.6 (0.8–3.5) 2.0 (0.9–4.2)
Delivery hospital type
 Level 3 Reference Reference Reference Reference
 Nonlevel 3 3.1 (1.8–5.2) d 4.8 (2.1–11.1) d 1.0 (0.7–1.4) 3.6 (2.7–4.9) d
Prenatal care insurance
 Private Reference Reference Reference Reference
 Government/other 1.3 (0.7–2.3) 1.9 (0.8–4.6) 1.1 (0.8–1.6) 1.2 (0.9–1.7)
Prenatal care initiation
 First trimester Reference Reference Reference Reference
 After first trimester 1.1 (0.5–2.3) 1.5 (0.6–3.4) 1.2 (0.9–1.7) 1.1 (0.8–1.6)
CCHD type
 Nonisolated Reference Reference Reference Reference
 Isolated e 2.0 (1.0–4.0) d 0.9 (0.4–2.2) 1.6 (1.0–2.5) d 1.6 (1.1–2.2) d
Gestational age, wk f
 ≥37 Reference Reference Reference Reference
 20–36 0.4 (0.1–1.2) 0.4 (0.1–1.8) 0.7 (0.4–1.2) 1.1 (0.8–1.7)
Plurality
 Singleton Reference Reference Reference Reference
 Multiple 1.0 (0.4–3.1) 3.1 (0.9–10.4) 1.2 (0.6–2.3) 1.4 (0.9–2.3)
Birth weight, g
 ≥1500 Reference Reference Reference Reference
 355–1499 1.2 (0.2–8.8) NA 0.5 (0.1–2.0) 1.1 (0.5–2.2)

NA, not applicable.

a

Adjusted model includes all demographic and clinical factors examined. Each individual variable is presented after controlling for all other variables in the model.

b

Diagnosed after discharge home following delivery.

c

Includes dextro-transposition of the great arteries, hypoplastic left heart syndrome, pulmonary atresia, tetralogy of Fallot, total anomalous pulmonary venous return, tricuspid atresia, and truncus arteriosus.

d

P < .05.

e

Includes cases with single CCHDs and cases with multiple cardiac defects.

f

Based on clinical estimate.