TABLE 2.
Comparison of the Frequency of Adverse Events in Term and Preterm Patients
| Adverse Event | Term | Preterm | All Children | P a |
|---|---|---|---|---|
| n | 56 542 | 685 | 57 227 | |
| None | 51 747 (91.5) | 584 (85.3) | 52 331 (91.4) | <.001 |
| Any complication | 4795 (8.5) | 101 (14.7) | 4896 (8.6) | <.001 |
| Airway obstruction | 1138 (2.0) | 20 (2.9) | 1158 (2.0) | .094 |
| Oxygen desaturation | 999 (1.8) | 31 (4.5) | 1030 (1.8) | <.001 |
| Coughing | 1092 (1.9) | 23 (3.4) | 1115 (2.0) | .007 |
| Secretions | 544 (1.0) | 18 (2.6) | 562 (1.0) | <.001 |
| Agitation | 263 (0.5) | 2 (0.3) | 265 (0.5) | .78b |
| Apnea | 470 (0.8) | 14 (2) | 484 (0.9) | .001 |
| IV related | 249 (0.4) | 5 (0.7) | 254 (0.4) | .24b |
| Hemodynamic changec | 160 (0.3) | 3 (0.4) | 163 (0.3) | .45b |
| Laryngospasm | 184 (0.3) | 1 (0.2) | 185 (0.3) | .73b |
| Vomiting | 137 (0.2) | 1 (0.2) | 138 (0.2) | 1.0b |
| Aspiration | 7 (0.01) | 1 (0.2) | 8 (0.01) | .09b |
| Stridor | 89 (0.2) | 1 (0.2) | 90 (0.2) | 1.0b |
| Unplanned admission | 17 (0.03) | 0 (0.0) | 17 (0.03) | 1.0b |
| Bronchospasm | 41 (0.1) | 1 (0.2) | 42 (0.1) | .40b |
| Allergic reaction | 11 (0.02) | 0 (0.0) | 11 (0.02) | 1.0b |
| Failed sedation | 93 (0.16) | 0 (0.0) | 93 (0.16) | .63b |
| Procedure not completed | 151 (0.3) | 1 (0.2) | 152 (0.3) | 1.0b |
| Emergent airway | 89 (0.2) | 1 (0.2) | 90 (0.2) | 1.0b |
| Emergency anesthesia consult | 12 (0.02) | 0 (0.0) | 12 (0.02) | 1.0b |
| Hypothermia | 5 (0.01) | 2 (0.3) | 7 (0.01) | .003b |
| Myoclonus | 54 (0.1) | 0 (0.0) | 54 (0.1) | 1.0b |
| Seizure | 16 (0.03) | 0 (0.0) | 16 (0.03) | 1.0b |
| Reversal agent | 2 (0.0) | 1 (0.2) | 3 (0.01) | .04b |
| Cardiac event | 4 (0.01) | 0 (0.0) | 4 (0.01) | 1.0b |
| Hiccups | 78 (0.1) | 1 (0.1) | 79 (0.1) | .6b |
| Snoring | 930 (1.6) | 19 (2.8) | 949 (1.7) | .02 |
| Death | 0 (0.0) | 0 (0.0) | 0 (0.0) | — |
Values are expressed as n (%) unless noted otherwise. P values <.05 were considered significant between the 2 groups. IV, intravenous line.
a
Pearson χ2.
b
Fisher exact tests reported.
c
Unexpected change in heart rate or blood pressure >30%.