TABLE 3.
Unadjusted and Adjusted ORs for the Development of Sedation/Anesthesia Adverse Events in the Preterm Category
| Event | Unadjusted OR | OR Adjusted for Age and Gender | ||
|---|---|---|---|---|
| OR (95% CI) | P | OR 95% CI | P | |
| Any adverse event | 1.87 (1.51–2.31) | <.001 | 1.93 (1.56–2.39) | <.001 |
| No adverse event | 0.54 (0.43–0.66) | <.001 | 0.52 (0.42–0.64) | <.001 |
| Airway obstruction | 1.46 (0.93 -2.3) | .10 | 1.58 (1.01–2.49) | .045 |
| Oxygen desaturation | 2.64 (1.83-3.80) | <.001 | 2.61 (1.81–3.76) | <.001 |
| Coughing | 1.76 (1.16-2.69) | .01 | 1.59 (1.04–2.43) | .03 |
| Secretions | 2.78 (1.73–4.48) | <.001 | 2.45 (1.52–3.95) | <.001 |
| Agitation | 0.63 (0.16–2.53) | .48 | 0.63 (0.16–2.54) | .52 |
| Apnea | 2.50 (1.46–4.28) | .001 | 3.08 (1.79–5.24) | <.001 |
| IV related | 1.66 (0.68–4.05) | .26 | 1.36 (0.56–3.30) | .51 |
| Hemodynamic change | 1.55 (0.49–4.87) | .43 | 1.98 (0.62–6.21) | .24 |
| Laryngospasm | 0.45 (0.63–3.20) | .42 | 0.44 (0.06–3.12) | .41 |
| Vomiting | 0.60 (0.08–4.27) | .61 | 0.71 (0.10–5.08) | .74 |
| Aspiration | 11.8 (1.5–96.1) | .02 | 13.2 (1.57–111.4) | .02 |
| Stridor | 0.93 (0.13–6.70) | .94 | 0.86 (0.12–6.06) | .26 |
| Bronchospasm | 2.03 (0.28–14.7) | .49 | 1.57 (0.21–11.5) | .66 |
| Emergent airway | 0.93 (0.13–6.70) | .94 | 0.95 (0.13–6.81) | .95 |
| Hypothermia | 33.1 (6.41–170.9) | <.001 | 20.7 (3.90–109.7) | <.001 |
| Reversal agent | 41.3 (3.74–456.3) | .002 | 46.8 (3.87–565.4) | .002 |
| Hiccups | 1.06 (0.15–7.62) | .96 | 1.03 (0.14–7.50) | .97 |
| Snoring | 1.71 (1.08–2.71) | .02 | 1.90 (1.21–3.02) | .01 |
Variables that predicted failure in the model were omitted. P values <0.05 for preterm variable were considered significant. IV, intravenous line.