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. 2022 Mar 22;38(2):384–395. doi: 10.1093/ndt/gfac134

Table 4.

FG models for all-cause death and KFRT

Four-variable model Six-variable model Seven-variable model
Analysis group and outcome Incidence rate (/1000 person-years) SHR (95% CI) P-value SHR (95% CI) P-value SHR (95% CI) P-value
Analysis A (n = 778)
All-cause death
 IgAN 2.5 Reference Reference Reference
 MN 14.5 2.91 (1.02, 8.30) 0.05 2.73 (0.96, 7.77) 0.06 2.54 (0.84, 7.70) 0.1
 FSGS 8.8 3.77 (1.09, 13.1) 0.04 3.63 (1.02, 13.0) 0.05 3.58 (1.06, 12.2) 0.04
 Crescentic GN 23.1 5.90 (2.05, 17.0) <0.001 5.69 (1.98, 16.3) <0.001 6.05 (2.13, 17.2) <0.001
 Classic DN 13.7 2.67 (0.70, 10.2) 0.2 2.45 (0.54, 11.2) 0.3 2.11 (0.44, 10.2) 0.4
 Nephrosclerosis 9.7 4.12 (1.11, 15.2) 0.03 3.98 (1.08, 14.7) 0.04 3.91 (1.16, 13.2) 0.03
KFRT
 IgAN 54.6 Reference Reference Reference
 MN 35.3 0.45 (0.24, 0.84) 0.01 0.43 (0.23, 0.81) 0.009 0.41 (0.22, 0.77) 0.006
 FSGS 70 0.82 (0.53, 1.26) 0.4 0.8 (0.51, 1.24) 0.3 0.86 (0.56, 1.35) 0.5
 Crescentic GN 40.4 0.82 (0.43, 1.56) 0.5 0.78 (0.40, 1.51) 0.5 0.79 (0.41, 1.51) 0.5
 Classic DN 137 1.42 (0.85, 2.38) 0.2 1.29 (0.73, 2.28) 0.4 1.23 (0.72, 2.11) 0.5
 Nephrosclerosis 61.2 0.96 (0.60, 1.53) 0.9 0.95 (0.59, 1.50) 0.8 0.95 (0.59, 1.52) 0.8
Analysis B (n = 1117)
All-cause death
 Biopsy-proven Classic DN 13.7 Reference Reference Reference
 Other biopsy-proven kidney diseases 13 1.14 (0.33, 3.92) 0.8 1.15 (0.34, 3.93) 0.8 1.12 (0.32, 3.97) 0.9
 No. of biopsy results 20.1 1.32 (0.43, 4.11) 0.6 1.33 (0.43, 4.14) 0.6 1.36 (0.43, 4.31) 0.6
KFRT
 Biopsy-proven Classic DN 137 Reference Reference Reference
 Other biopsy-proven kidney diseases 60.7 0.62 (0.39, 0.97) 0.04 0.62 (0.39, 0.98) 0.04 0.72 (0.45, 1.16) 0.2
 No. of biopsy results 84.4 0.72 (0.49, 1.05) 0.09 0.72 (0.49, 1.06) 0.09 0.79 (0.53, 1.17) 0.3

Multivariable models were adjusted for age sex, eGFR and lnUACR (four-variable model), plus hypertension and DM (six-variable model), and the four-variable model plus serum calcium, phosphate and albumin (seven-variable model). Values in bold are statistically significant.