Table 4.
FG models for all-cause death and KFRT
| Four-variable model | Six-variable model | Seven-variable model | |||||
|---|---|---|---|---|---|---|---|
| Analysis group and outcome | Incidence rate (/1000 person-years) | SHR (95% CI) | P-value | SHR (95% CI) | P-value | SHR (95% CI) | P-value |
| Analysis A (n = 778) | |||||||
| All-cause death | |||||||
| IgAN | 2.5 | Reference | Reference | Reference | |||
| MN | 14.5 | 2.91 (1.02, 8.30) | 0.05 | 2.73 (0.96, 7.77) | 0.06 | 2.54 (0.84, 7.70) | 0.1 |
| FSGS | 8.8 | 3.77 (1.09, 13.1) | 0.04 | 3.63 (1.02, 13.0) | 0.05 | 3.58 (1.06, 12.2) | 0.04 |
| Crescentic GN | 23.1 | 5.90 (2.05, 17.0) | <0.001 | 5.69 (1.98, 16.3) | <0.001 | 6.05 (2.13, 17.2) | <0.001 |
| Classic DN | 13.7 | 2.67 (0.70, 10.2) | 0.2 | 2.45 (0.54, 11.2) | 0.3 | 2.11 (0.44, 10.2) | 0.4 |
| Nephrosclerosis | 9.7 | 4.12 (1.11, 15.2) | 0.03 | 3.98 (1.08, 14.7) | 0.04 | 3.91 (1.16, 13.2) | 0.03 |
| KFRT | |||||||
| IgAN | 54.6 | Reference | Reference | Reference | |||
| MN | 35.3 | 0.45 (0.24, 0.84) | 0.01 | 0.43 (0.23, 0.81) | 0.009 | 0.41 (0.22, 0.77) | 0.006 |
| FSGS | 70 | 0.82 (0.53, 1.26) | 0.4 | 0.8 (0.51, 1.24) | 0.3 | 0.86 (0.56, 1.35) | 0.5 |
| Crescentic GN | 40.4 | 0.82 (0.43, 1.56) | 0.5 | 0.78 (0.40, 1.51) | 0.5 | 0.79 (0.41, 1.51) | 0.5 |
| Classic DN | 137 | 1.42 (0.85, 2.38) | 0.2 | 1.29 (0.73, 2.28) | 0.4 | 1.23 (0.72, 2.11) | 0.5 |
| Nephrosclerosis | 61.2 | 0.96 (0.60, 1.53) | 0.9 | 0.95 (0.59, 1.50) | 0.8 | 0.95 (0.59, 1.52) | 0.8 |
| Analysis B (n = 1117) | |||||||
| All-cause death | |||||||
| Biopsy-proven Classic DN | 13.7 | Reference | Reference | Reference | |||
| Other biopsy-proven kidney diseases | 13 | 1.14 (0.33, 3.92) | 0.8 | 1.15 (0.34, 3.93) | 0.8 | 1.12 (0.32, 3.97) | 0.9 |
| No. of biopsy results | 20.1 | 1.32 (0.43, 4.11) | 0.6 | 1.33 (0.43, 4.14) | 0.6 | 1.36 (0.43, 4.31) | 0.6 |
| KFRT | |||||||
| Biopsy-proven Classic DN | 137 | Reference | Reference | Reference | |||
| Other biopsy-proven kidney diseases | 60.7 | 0.62 (0.39, 0.97) | 0.04 | 0.62 (0.39, 0.98) | 0.04 | 0.72 (0.45, 1.16) | 0.2 |
| No. of biopsy results | 84.4 | 0.72 (0.49, 1.05) | 0.09 | 0.72 (0.49, 1.06) | 0.09 | 0.79 (0.53, 1.17) | 0.3 |
Multivariable models were adjusted for age sex, eGFR and lnUACR (four-variable model), plus hypertension and DM (six-variable model), and the four-variable model plus serum calcium, phosphate and albumin (seven-variable model). Values in bold are statistically significant.