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. 2023 Jan 25;66(3):1972–1989. doi: 10.1021/acs.jmedchem.2c01767

Scheme 8. Synthetic Route for Compound 26.

Scheme 8

Reagents and conditions: (a) 2-bromoethyl 4-methylbenzenesulfonate, Cs2CO3, DMF, rt, 16 h; and (b) amine, DMF, microwave 100 °C, 30 min.