Table 2.
Drug classes implicated in ADRs according to the WHO-ATC classification system (n = 159 study participants)
| WHO-ATC class | ADRs, n | % all ADRs | |
|---|---|---|---|
| A | Alimentary tract and metabolism | 18 | 8.53 |
| A02 | Drugs for acid-related disorders | 10 | 4.74 |
| A07 | Antidiarrhoeal, intestinal anti-inflammatory/anti-infective agents | 1 | 0.47 |
| A10 | Drugs used in diabetes | 5 | 2.37 |
| A11 | Vitamins | 1 | 0.47 |
| A12 | Mineral supplements | 1 | 0.47 |
|
| |||
| B | Blood and blood forming organs | 4 | 1.90 |
| B01 | Antithrombotic agents | 3 | 1.42 |
| B03 | Antianaemic preparations | 1 | 0.47 |
|
| |||
| C | Cardiovascular system | 69 | 32.70 |
| C01 | Cardiac therapy | 5 | 2.37 |
| C02 | Antihypertensives | 2 | 0.95 |
| C03 | Diuretics | 13 | 6.16 |
| C07 | Beta blocking agents | 4 | 1.90 |
| C08 | Calcium channel blockers | 17 | 8.06 |
| C09 | Agents acting on the renin-angiotensin system | 19 | 9.00 |
| C10 | Lipid-modifying agents | 9 | 4.27 |
|
| |||
| G | Genito-urinary system and sex hormones | 10 | 4.74 |
| G04 | Urologicals | 10 | 4.74 |
|
| |||
| H | Systemic hormonal preparations, excluding sex hormones and insulins | 4 | 1.90 |
| H03 | Thyroid therapy | 3 | 1.42 |
| H05 | Calcium homeostasis | 1 | 0.47 |
|
| |||
| J | Anti-infectives for systemic use | 26 | 12.32 |
| J01 | Antibacterials for systemic use | 26 | 12.32 |
|
| |||
| L | Antineoplastic and immunomodulating agents | 1 | 0.47 |
| L04 | Immunosuppressants | 1 | 0.47 |
|
| |||
| M | Musculoskeletal system | 14 | 6.64 |
| M01 | Anti-inflammatory and antirheumatic products | 10 | 4.74 |
| M05 | Drugs for treatment of bone diseases | 4 | 1.90 |
|
| |||
| N | Nervous system | 61 | 28.91 |
| N01 | Anaesthetics | 4 | 1.90 |
| N02 | Analgesics | 28 | 13.27 |
| N03 | Antiepileptics | 7 | 3.32 |
| N04 | Anti-Parkinson’s drugs | 1 | 0.47 |
| N05 | Psycholeptics | 4 | 1.90 |
| N06 | Psychoanaleptics | 16 | 7.58 |
| N07 | Other nervous system drugs | 1 | 0.47 |
|
| |||
| R | Respiratory system | 4 | 1.90 |
| R03 | Drugs for obstructive airway diseases | 2 | 0.95 |
| R06 | Cough and cold preparations | 2 | 0.95 |
ADR = adverse drug reaction. WHO-ATC = World Health Organization Anatomical Therapeutic Code.