How this fits in

There is a bidirectional association between depression and type 2 diabetes (T2DM), therefore the treatment of each is important to the other. However, the use of multiple medications, or polypharmacy, may increase the risk of drug interactions, side effects, and poor adherence. Polypharmacy is common in individuals with T2DM, yet the impact of polypharmacy on antidepressant use in individuals with T2DM is unknown. This study revealed that individuals with higher levels of polypharmacy may be more adherent to antidepressant treatment, potentially owing to more severe depression and thereby an increased need for treatment.