Table 3.
LA parameters in control group and hypertrophic obstructive cardiomyopathy group before and after myectomy
| Parameter | Premyectomy (n = 88) | Postmyectomy (n = 88) | Healthy controls (n = 86) | P value for premyectomy vs. postmyectomy |
|---|---|---|---|---|
| LA structural parameter | ||||
| LA anteroposterior diameter (mm) | 41 ± 8† | 37 ± 8† | 28 ± 6 | < 0.001 |
| LA left–right diameter (mm) | 70 (63, 76)† | 63 (58, 70)† | 57 (51, 62) | < 0.001 |
| LA Vmax index (ml/m2) | 69.3 ± 25.9† | 50.0 ± 16.2† | 36.9 ± 8.4 | < 0.001 |
| LA Vpac index (ml/m2) | 48.4 (38.1, 71.2)† | 38.3 (32.2, 44.9)† | 23.4 (20.2, 26.9) | < 0.001 |
| LA Vmin index (ml/m2) | 42.2 ± 24.4† | 26.4 ± 15.8† | 13.4 ± 4.1 | < 0.001 |
| LA reservoir function | ||||
| LA total EF (%) | 42.5 ± 12.5† | 49.4 ± 11.7† | 64.0 ± 5.4 | < 0.001 |
| εs (%) | 21.0 ± 9.8† | 25.6 ± 9.5† | 43.0 ± 9.0 | < 0.001 |
| SRs (1/s) | 0.77 (0.53, 1.10)† | 0.88 (0.67, 1.22)† | 1.50 (1.33, 1.72) | 0.003 |
| LA conduit function | ||||
| LA passive EF (%) | 18.5 ± 9.1† | 19.6 ± 8.7† | 33.8 ± 8.7 | 0.31 |
| εe (%) | 9.2 (5.8, 13.5)† | 10.0 (7.0, 13.1)† | 22.3 (17.9, 29.9) | 0.21 |
| SRe (1/s) | − 0.48 (− 0.32, − 0.74)† | − 0.58 (− 0.41, − 0.77)† | − 1.33 (− 1.11, − 1.75) | 0.007 |
| LA booster pump function | ||||
| LA booster EF (%) | 29.7 ± 11.7† | 37.5 ± 10.8† | 45.4 ± 6.4 | < 0.001 |
| εa (%) | 9.9 (6.0, 14.2)† | 14.3 (11.0, 18.2)† | 19.2 (16.6, 22.8) | < 0.001 |
| SRa (1/s) | − 0.83 (− 0.54, − 1.26)† | − 1.17 (− 0.86, − 1.52)† | − 1.72 (− 1.47, − 2.10) | < 0.001 |
Values are presented as mean ± standard deviations or median (interquartile range)
LA left atrial, EF emptying fraction
†Indicating P value < 0.05 for patients with hypertrophic obstructive cardiomyopathy versus healthy participants