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. 2023 Jan 30;12:1065716. doi: 10.3389/fonc.2022.1065716

Table 1.

Patient characteristics.

Characteristics Total Underweight Normal-weight Overweight
Age, median (IQR), y 60.0 (53-67) 59.0 (54-70) 60.0 (52-67) 61.0 (54-67)
Male 385 (71.2%) 17 (58.6%) 225 (66.8%) 143 (81.7%)
BMI, median (IQR), kg/m² 23.4 (21.3-25.6) 17.4 (16.6-18.0) 22.2 (20.9-23.7) 26.4 (25.7-28.1)
Tobacco
 Never 291 (53.8%) 15 (51.7%) 188 (55.8%) 88 (50.3%)
 Former 115 (21.3%) 5 (17.2%) 71 (21.1%) 39 (22.3%)
 Current 135 (25.0%) 9 (31.0%) 78 (23.1%) 48 (27.4%)
Neoadjuvant chemotherapy 157 (29.0%) 8 (27.6%) 104 (30.9%) 45 (25.7%)
Tumor location
 Lower third 290 (53.6%) 17 (58.6%) 193 (57.3%) 80 (45.7%)
 Middle third 147 (27.2%) 4 (13.8%) 95 (28.2%) 48 (27.4%)
 Upper third 104 (19.2%) 8 (27.6%) 49 (14.5%) 47 (26.9%)
Tumor size, median (IQR), cm 3.0 (2.0-4.0) 3.5 (2.5-5.2) 3.0 (2.0-4.5) 2.5 (2.0-4.0)
Tumor grade
Poorly  differentiated 377 (69.7) 21 (72.4) 244 (72.4) 112 (64.0)
 Well-moderately differentiated 164 (30.3) 8 (27.6) 93 (27.6) 63 (36.0)
T stage
 T1 186 (34.4) 8 (27.6) 106 (31.5) 72 (41.1)
 T2 86 (15.9) 4 (13.8) 54 (16.0) 28 (16.0)
 T3 170 (31.4) 11 (37.9) 105 (31.2) 54 (30.9)
 T4 99 (18.3) 6 (20.7) 72 (21.4) 21 (12.0)
Lymph node metastasis
 No 286 (52.9) 12 (41.4) 164 (48.7) 110 (62.9)
 Yes 255 (47.1) 17 (58.6) 173 (51.3) 65 (37.1)
Distant metastasis
 No 530 (98.0) 28 (96.6) 329 (97.6) 173 (98.9)
 Yes 11 (2.0) 1 (3.4) 8 (2.4) 2 (1.1)
TNM Stage
 I 220 (40.7%) 8 (27.6%) 124 (36.8%) 88 (50.3%)
 II 146 (27.0%) 9 (31.0%) 97 (28.8%) 40 (22.9%)
 III 164 (30.3%) 11 (37.9%) 108 (32.0%) 45 (25.7%)
 IV 11 (2.0%) 1 (3.4%) 8 (2.4%) 2 (1.1%)
Postoperative complications
 No 419 (77.4) 25 (86.2) 270 (80.1) 124 (70.9)
 Yes 122 (22.6) 4 (13.8) 67 (19.9) 51 (29.1)
Adjuvant chemotherapy 314 (58.0) 13 (44.8) 208 (61.7) 93 (53.1)
Baseline splenic volume, median (IQR), ml 167.0 (124.9-224.6) 121.3 (86.9-153.5) 159.7 (119.1-203.6) 206.5 (154.1-252.4)