Table 3.

Multivariate Cox analysis for OS in overweight patients.

Variable		HR (univariable)	HR (multivariable)
Age, y		1.05 (1.01-1.09, p=0.026)	1.07 (1.02-1.12, p=0.007)
Sex	Female	[Reference]	[Reference]
	Male	2.32 (0.71-7.63, p=0.164)	1.45 (0.34-6.16, p=0.614)
BMI, kg/m²		0.93 (0.77-1.12, p=0.451)	0.91 (0.73-1.12, p=0.372)
Tobacco	Never	[Reference]	[Reference]
	Former	0.85 (0.30-2.35, p=0.749)	0.88 (0.29-2.65, p=0.817)
	Current	2.00 (0.94-4.27, p=0.072)	2.05 (0.88-4.78, p=0.097)
Tumor location	Lower third	[Reference]	[Reference]
	Middle thrid	3.34 (1.23-9.03, p=0.018)	3.67 (1.11-12.18, p=0.034)
	Upper third	4.77 (1.85-12.33, p=0.001)	5.26 (1.62-17.14, p=0.006)
Tumor size, cm		1.29 (1.10-1.50, p=0.002)	1.12 (0.92-1.36, p=0.262)
Tumor grade	Poorly differentiated	[Reference]	[Reference]
	Well-moderately differentiated	0.56 (0.25-1.25, p=0.157)	0.77 (0.31-1.88, p=0.565)
TNM Stage	I	[Reference]	[Reference]
	II	2.69 (0.90-8.00, p=0.076)	2.20 (0.69-7.05, p=0.185)
	III	6.74 (2.65-17.12, p<0.001)	6.23 (2.09-18.58, p=0.001)
	IV	44.97 (8.75-231.03, p<0.001)	91.89 (11.62-726.88, p<0.001)
Postoperative complication	No	[Reference]	[Reference]
	Yes	1.60 (0.78-3.28, p=0.197)	1.56 (0.67-3.63, p=0.299)
Splenic volume	< 185 ml	[Reference]	[Reference]
	≥ 185 ml	2.80 (1.21-6.47, p=0.016)	3.55 (1.36-9.26, p=0.010)