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. 2023 Feb 9;66(4):2663–2680. doi: 10.1021/acs.jmedchem.2c01627

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Scheme 2 — Reagents and conditions: (a) 16(27) or 17, COMU,⁵⁵ NMM, DMF/CH₂Cl₂, 0 °C to rt, 14 and 13%, respectively; (b) COMU,⁵⁵ NMM, DMF/CH₂Cl₂, 0 °C to rt, 33%.