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. Author manuscript; available in PMC: 2023 Feb 13.
Published in final edited form as: Mat Matters (Milwaukee). 2022;17(2):29–36.

Figure 2.

Figure 2.

Macrophage-targeting nanoparticles stimulate anti-GBM immunity and prolong survival of GBM-bearing mice. A) In vivo fluorescence imaging and confocal laser scanning microscopy imaging indicates enhanced brain distribution and macrophage/microglia uptake of miRNA in the brain through virus-mimic nanoparticle-mediated delivery post-intravenous injection. Reproduced with permission from reference 6, copyright 2021 John Wiley and Sons. B) Kaplan-Meier animal survival curves and sequential bioluminescence imaging of brain tumors indicate the therapy efficacy of IRF5-inducing nanoparticles when combined with radiotherapy. Reproduced from reference 5, copyright 2019 Springer Nature. Open access article distributed under the terms of the Creative Commons CC BY license.