Table 1.
Quality parameters obtained for 11 pharmaceuticals ordered following de ATC code. DXM dexamethasone, PRED prednisone, LEV levofloxacin, CIP ciprofloxacin, RDV remdesivir, RTV ritonavir, LPV lopinavir, APAP acetaminophen, HCQ hydroxychloroquine, CHQ chloroquine, CPS cloperastine
| Compound | Linearity (µg L−1) | R2 | IDL (pg) | Intra-day precision (%) | %R ± RSD | MDL (ng L−1) | LOQ (ng L−1) | Matrix effect (%) |
|---|---|---|---|---|---|---|---|---|
| Dexamethasone | 0.001–2.5 | 0.9989 | 20.8 | 7 | 52 ± 8 | 24 | 80 | 41 |
| Prednisone | 0.001–2.5 | 0.9994 | 6.82 | 1 | 65 ± 2 | 14 | 47 | 60 |
| Ciprofloxacin | 0.001–2.5 | 0.9899 | 12.3 | 6 | 89 ± 7 | 7 | 59 | 62 |
| Levofloxacin | 0.001–2.5 | 0.9933 | 10.0 | 9 | 40 ± 2 | 5 | 16 | 31 |
| Remdesivir | 0.001–2.5 | 0.9996 | 4.57 | 8 | 45 ± 3 | 6 | 20 | 46 |
| Ritonavir | 0.001–2.5 | 0.9970 | 16.4 | 1 | 91 ± 2 | 7 | 24 | 106 |
| Lopinavir | 0.001–2.5 | 0.9998 | 5.82 | 6 | 58 ± 1 | 1 | 4 | 60 |
| Acetaminophen | 0.001–2.5 | 0.9934 | 12.8 | 5 | 71 ± 7 | 12 | 39 | 56 |
| Hydroxychloroquine | 0.05–2.5 | 0.9750 | 5.33 | 1 | 78 ± 4 | 4 | 12 | 64 |
| Chloroquine | 0.05–2.5 | 0.9948 | 5.38 | 1 | 33 ± 11 | 2 | 8 | 37 |
| Cloperastine | 0.001–2.5 | 0.9980 | 21.2 | 11 | 77 ± 5 | 3 | 11 | 55 |