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. 2023 Feb 13;68(3):337–353. doi: 10.1007/s12223-022-01030-y

Table 1.

Anti-inflammatory properties of Lactic acid bacterial strains

Strains Anti-inflammatory properties References
Ligilactobacillus salivarius ssp. salivarius CECT5713

Inflamed tissue recovery in rat colitis TNBS model,

Improvement in the production of proinflammatory cytokines and iNOS (inducible NO synthase) expression

(Peran et al. 2005)
Lactobacillus pentosus

Alleviate ulcerative colonic inflammation caused by DSS in murine model

Beneficial for regulation of intestinal Immunity

Encourages the growth of beneficial bacterial metabolites like pantothenic acid

(Ma et al. 2020)
Lactobacillus curvatus WiKim38

Increased IL 10 levels in bone marrow–derived dendritic cells

Activation of NF-κB and ERK

(Ma et al. 2020)
Pediococcus acidilactici Suppressed the IL-8 production by Enterococcus faecalis in human intestinal epithelial cells (Yoon and Kang 2020)
Bacillus amyloliquefaciens SCGB1 Upregulated IL-10 production and downregulated IL-6 production in macrophage cell line induced with LPS (Kang et al. 2021)
Lacticaseibacillus casei Upregulation of anti-inflammatory cytokines and downregulation of proinflammatory cytokines on shigella induced human epithelial cells (Tien et al. 2006)
Lactobacillus gasseri NCi501 Reduced inflammation in IL-10 deficient mice (Carroll et al. 2007)

iNOS inducible NO synthase, NF-KB nuclear factor kappa light chain enhancer of activated B cells, ERK extracellular signal regulated kinase pathway, IL interleukin, LPS lipopolysaccharide, TNBS trinitrobenzenesulfonic acid