Skip to main content
. 2021 Dec 1;3(1):66–81. doi: 10.1158/2643-3230.BCD-21-0095

Figure 1.

Figure 1. Comparisons of the sensitivity of MFC-MRD and NGS-MRD from peripheral blood and BM. Vertical and horizonal dotted lines represent the sensitivity cutoff for MFC and NGS, respectively. A, MFC-MRD from blood (y-axis) compared with samples from the same time point obtained from BM (x-axis); n = 450. B, NGS-MRD from blood (y-axis) compared with samples from the same time point obtained from BM (x-axis); n = 66. C, NGS-MRD from BM (y-axis) compared with MFC-MRD from BM (x-axis) in all matched samples; n = 280. D, NGS-MRD from blood (y-axis) compared with MFC-MRD from BM (x-axis) in all matched samples; n = 77. E, NGS-MRD compared with MFC-MRD in all matched samples with an NGS sensitivity cutoff of 10−4. F, NGS-MRD compared with MFC-MRD in all matched samples with an NGS sensitivity cutoff of 10−6. E and F, Green, red, blue, and purple dots represent baseline index clones, NGS-MRD−, NGS-MRD+, and NGS-MRD indeterminate (insufficient number of cells to determine MRD), respectively.

Comparisons of the sensitivity of MFC-MRD and NGS-MRD from peripheral blood and BM. Vertical and horizonal dotted lines represent the sensitivity cutoff for MFC and NGS, respectively. A, MFC-MRD from blood (y-axis) compared with samples from the same time point obtained from BM (x-axis); n = 450. B, NGS-MRD from blood (y-axis) compared with samples from the same time point obtained from BM (x-axis); n = 66. C, NGS-MRD from BM (y-axis) compared with MFC-MRD from BM (x-axis) in all matched samples; n = 280. D, NGS-MRD from blood (y-axis) compared with MFC-MRD from BM (x-axis) in all matched samples; n = 77. E, NGS-MRD compared with MFC-MRD in all matched samples with an NGS sensitivity cutoff of 10−4. F, NGS-MRD compared with MFC-MRD in all matched samples with an NGS sensitivity cutoff of 10−6. E and F, Green, red, blue, and purple dots represent baseline index clones, NGS-MRD−, NGS-MRD+, and NGS-MRD indeterminate (insufficient number of cells to determine MRD), respectively.